[HTML][HTML] Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

A Inglis, R Ubungen, S Farooq, P Mata, J Thiam… - BMC genomics, 2021 - Springer
Obesity is a major risk factor for type 2 diabetes, and the … consist of catecholamines,
neuropeptides and also micro RNAs … gland loss of CHGB in knockout mice was shown to reduce …

Diabetes type 2 and kisspeptin: central and peripheral sex-specific actions

M Dudek, K Ziarniak, ML Cateau, L Dufourny… - Trends in Endocrinology …, 2019 - cell.com
… Finally, sex differences in body fat distribution exist that … negative feedback at the hypophyseal
and hypothalamic levels but … organs including fat, pancreas, stomach, and liver (Figure I). …

Sex differences in behavioral and metabolic effects of gene inactivation: The neuropeptide Y and Y receptors in the brain

C Eva, A Oberto, A Longo, P Palanza… - … & Biobehavioral Reviews, 2020 - Elsevier
… among the various strains of genetically modified mice and to … pancreatic polypeptides,
that includes peptide YY (PYY) and … /high fat diet (MHF) to male TgY1R/LacZ mice, increased …

[HTML][HTML] Murine models of obesity

T Martins, C Castro-Ribeiro, S Lemos, T Ferreira… - Obesities, 2022 - mdpi.com
… The Tsumura and Suzuki obesity and diabetes (TSOD) strain … of eating, such as the
neuropeptide Y and leptin, are also … with mild renal damage and increased pancreatic islet mass …

Emerging roles for kisspeptin in metabolism

C Izzi‐Engbeaya, WS Dhillo - The Journal of Physiology, 2022 - Wiley Online Library
… Kisspeptin, a neuropeptide hormone, has been firmly … (including women, people with obesity
and people with diabetes). … A, Pancreas-specific kisspeptin receptor knockout mice develop …

Obesity, POMC, and POMC-processing enzymes: surprising results from animal models

I Lindberg, LD Fricker - Endocrinology, 2021 - academic.oup.com
… are not detected in mouse hypothalamus or pituitary, although a … Because PC1/3 and CPE
process many neuropeptide and … peptidergic differences between these 2 different pancreatic

[HTML][HTML] Sexual dimorphism in adipose-hypothalamic crosstalk and the contribution of aryl hydrocarbon receptor to regulate energy homeostasis

N Haque, SA Tischkau - International journal of molecular sciences, 2022 - mdpi.com
… Overall, this review summarizes sex differences in the … the pancreas circulate in the blood in
proportion to fat mass … CRH induces anorexia in the brain by inhibiting neuropeptide Y (NPY)…

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
… –pituitary–gonadal (HPG) axis and decreases fat mass. … of major appetite-regulating
neuropeptides, with higher agouti-… kisspeptin levels within the pancreas would help to advance …

Rodent models of obesity

M Doulberis, A Papaefthymiou, SA Polyzos… - Minerva …, 2020 - zora.uzh.ch
sexual difference can be interpreted, due to different gonadal … destruction of pancreatic β-cells
27,28,67. For induction of … precursors, including neuropeptides and hormones participated …

[HTML][HTML] A systematic review on different models of inducing obesity in animals: Advantages and limitations

JB Suleiman, M Mohamed… - Journal of advanced …, 2020 - ncbi.nlm.nih.gov
… that the obese mice had enlargement of the pancreas and … TSOD includes TSOD strain,
which is obese with diabetes … Meanwhile, mice with knockout of neuropeptide-Y 1 receptor (…